Protein Info for PP_1566 in Pseudomonas putida KT2440

Annotation: Peptidase U35

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF04586: Peptidase_S78" amino acids 16 to 170 (155 residues), 145.9 bits, see alignment E=6.5e-47 TIGR01543: phage prohead protease, HK97 family" amino acids 26 to 166 (141 residues), 114 bits, see alignment E=3.2e-37

Best Hits

KEGG orthology group: K06904, (no description) (inferred from 100% identity to ppu:PP_1566)

Predicted SEED Role

"Gene Transfer Agent prohead protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88MK5 at UniProt or InterPro

Protein Sequence (233 amino acids)

>PP_1566 Peptidase U35 (Pseudomonas putida KT2440)
MRHKDRLAAVKYRSFDYDVKAVGDDGLFSGYGSVFGVVDSYNEVVAPGAFLESIAEAKAK
GRTFPVLWQHRTGEPIGSWNIESLKEDDRGLFGEGGLWLADAPYARIAHRGMQTRSITGL
SIGYYVRESSFDEKTRIRTLTKLDLIEISIVTVPANDEARTDTIKSKLAHGGLPSMPEFE
LLLREAGFSKTQSAVIANRGLQHLLRSESAGDLAELEIVEALKSRPALSLPSF