Protein Info for PP_1449 in Pseudomonas putida KT2440

Annotation: conserved exported protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1508 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF05860: TPS" amino acids 46 to 288 (243 residues), 118.2 bits, see alignment E=6.3e-38 TIGR01901: filamentous hemagglutinin family N-terminal domain" amino acids 68 to 158 (91 residues), 51 bits, see alignment 5.2e-18 PF13332: Fil_haemagg_2" amino acids 368 to 428 (61 residues), 15.9 bits, see alignment (E = 1.2e-06) amino acids 593 to 750 (158 residues), 32.8 bits, see alignment E=7.6e-12 amino acids 785 to 861 (77 residues), 17 bits, see alignment 5.4e-07 amino acids 914 to 1060 (147 residues), 29.5 bits, see alignment E=7.6e-11 amino acids 1054 to 1157 (104 residues), 16.1 bits, see alignment 1.1e-06 amino acids 1091 to 1231 (141 residues), 31.2 bits, see alignment E=2.4e-11 amino acids 1175 to 1330 (156 residues), 53.5 bits, see alignment E=3.2e-18

Best Hits

KEGG orthology group: K11016, hemolysin (inferred from 100% identity to ppu:PP_1449)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88MW9 at UniProt or InterPro

Protein Sequence (1508 amino acids)

>PP_1449 conserved exported protein of unknown function (Pseudomonas putida KT2440)
MQTLSQLPPVRPDTLRWAIFLAVLGPSAALAQTGLEAASGPGGTPVIHNGHGVPVIDIVP
PNATGLSHNQFIDYNVATPGLVLNNATAAGQSQLAGALAANPQFQGQAASTILNEVISRN
ASLIEGPQEIFGRPADYILANPNGITLNGGSFINTTRAGFVVGTPQFEEQQLRYLDTLTA
SGTLQVLEYGQGNAGGALELIAPRVDSKGLLMASETLDITVGRNRIDSRSGEVVEHLPSP
STSIDASLFGAMRAGRIRVVSTTEGAGVRVGASQILGTEGVDISSAGGLHVSGSGDRPTE
LRSERGVLKLTAADDLMLETVDGQAPRIEARAGKKLTLDAKTIEHIKHDSDSWNKKFWFV
TRETYNRKTTTTHKQQQGSQLLGTESVLLQSGDDMRMTAAKVDAGNELTVDSGAGLDILA
GIDSKRTEQQVRHRKDLWRGDSDSDQLKETAKGSTLSAGHMSIKASDNLNVQGSSLHSRS
DLAIQAKQADIGTTTLQEHGTQRDYRGDLVSGTFFGDRKGNDTEGQVVAGSTITSDGELT
VSADQVTIKGSTVFGKQDAVLYSENGSLAIEADHGSTTSTQRTSDSKLFGLIGSKHESTD
RKQQVLVSDVSSTSNLRLASAEEMRIQGAKVEAGKHLQVEAKGDLLIGSAQSVDERETRD
QQRGFTANARQTQEAEDGKPESRQYAAGVAYEVVTSTSKQRTTNQVASELKGASVGMNSS
AHLQVNGSKVQATAGDLDVQAREVTLGATRNDRDVATSTTESGGGLTVTGGIDRLGSLFE
GHHNREVQADRDSKVQRSELQASGDLKLRSDALLTEAAHVEAGNTLQVTAKRIDNRAAQD
THEHEQSRDDWSGSLGASIEYRDLTRPIERLVLGEEAPRFQQASPEDAMAPPSVGADMTV
EHLKRLENQRRGIAQVSELSAAKVEVKADTLADQGTAWRANAGSLKIEAQQHQVSAAENT
QETTVQRLAYGGDARLDTSTGEDLNVRAAGKGGSLDKKDTASTAVPGSLYGQQGIQVQLG
SDGRYEGARIDGGEGSVVMHSAGSLALPQATDKAEQQSRQLDGNAWAKVGNRPGSTGVDG
RGYLDHGQKLSTQGKAQVAQIDAKGEVKLTSTGDLLLEGTRIGSREAKAGDIQVQSGGQL
QVKAASNTQQATGSNLGGGMELAAKAGQTQGGAIGGHFSHGKQDEHARQAVDAQFASNGT
LTLTSSAREDIALHLQGLQASAEQITLDASNGGMLVEASSSQERRDNLDISAGAGFNMAK
GALDTRGLHGRLKVELDKRDNLTWNTSDLRAERIDLQSRGDTRIESATLDAGHIGGTIDG
DLRIASLKDNVNTLSVKGDVRLSQEKNPQGYVNAAKSVAGPLGGKVEKKAGSALSKADPG
FSPTVSLDVSHAQRDNVARQTTLKSSDGIDLQVGGNAHLVGARLQSAKGDVRLDANSVTQ
ETLSGNDYRRDLSLDASNSPVDLGTAIAEIAKSKMAADGENALDLGVLRTSGHSRSEQWV
SSMQGKKH