Protein Info for PP_1108 in Pseudomonas putida KT2440

Annotation: Acyl-homoserine lactone acylase QuiP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 813 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01804: Penicil_amidase" amino acids 52 to 797 (746 residues), 588.1 bits, see alignment E=2e-180

Best Hits

Swiss-Prot: 100% identical to QUIP_PSEPK: Acyl-homoserine lactone acylase QuiP (quiP) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: None (inferred from 100% identity to ppu:PP_1108)

Predicted SEED Role

"Penicillin acylase (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.11

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88NU6 at UniProt or InterPro

Protein Sequence (813 amino acids)

>PP_1108 Acyl-homoserine lactone acylase QuiP (Pseudomonas putida KT2440)
MAAPAFPPFRLRFATAATLLGMLGLAGCQTGGYQDSVPPTSGVQPLKGLAQNVSVRRNAM
GAPLIESSSFHDALFSLGYVHAGDRIEQMVAMRLLAQGRLAELAGSEALDIDRLMRAANL
KQSAAQQYADASPRLKRFFEVYARGVNAYLFRYRDKLPAGLASSGYRPEYWKPEDSALIF
CLYAFSQSVNLQEELSALTLAQKAGSDKLAWLLPGAPDEPLAEMEVDKLKGLNLASQLPG
LPALAAASQKLADLDLLGSPGSANLALGPQRSRSGKSLLASDSRAAWALSPVQINTSKYQ
VAGLSLPGLPIVLAGYNGKLAWSSSAVMADNQDLFLEQLRRQGSQLSYLADGKWLPARAR
SETYFVRGQRPVREVMYDTRHGTLLAQPENASLGLALNLPQFKGDRSLDALFDLTRAKNV
ERAFDSTREVTAAAVNFVFAEPEHIGWQVSGRYPNRREGQGLLPSPGWDGRYDWDGYADP
MLHPYDQDPPAGWIGHANQRSLPRGYGMQLSSTWYYPERAERLAQLAGNGRHDSRSLMAL
QNDQVTLLANKLKQMFDAPGMAQPLKQAIDALPAGQRDKARDTLARLKAFDGRLSPVSAD
AALYELFLQEVARQTFLDDLGPESGPAWQAFVGNARLSFSAQADHLLGRDDSPFWDDRNT
PQKEDKPAILARSLAGAMEAGIAQLGADRRTWQWGKLHQYRWPAPAYHGLGDAISRSPLA
AGGDFTTLALTPFAWGSDFDTHLPASARMIVDFGQAEPLQILTSSGQSGNPASAHYRDGL
DAWFKGRFMSLPLQQQNFGRAYGNQRLTLVPGR