Protein Info for PP_1065 in Pseudomonas putida KT2440

Annotation: membrane protein required for efficient alginate biosynthesis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 111 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details PF06942: GlpM" amino acids 5 to 111 (107 residues), 162.2 bits, see alignment E=2.4e-52

Best Hits

Swiss-Prot: 81% identical to GLPM_PSEAE: Membrane protein GlpM (glpM) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02442, membrane protein GlpM (inferred from 99% identity to ppf:Pput_1106)

Predicted SEED Role

"Membrane protein glpM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88NY8 at UniProt or InterPro

Protein Sequence (111 amino acids)

>PP_1065 membrane protein required for efficient alginate biosynthesis (Pseudomonas putida KT2440)
MDLVFKAALGAGVVLLLAVLSKTRNYYIAGLVPLFPTFALIAHYIVGKGRSIADLKTTIL
FGMWSIIPYFVYLATLYVLVDRLRLEASMALATVAWLIAATVLVTVWVRMH