Protein Info for PP_1018 in Pseudomonas putida KT2440

Annotation: mannose/glucose ABC transporter - ATP binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 PF00005: ABC_tran" amino acids 21 to 163 (143 residues), 122.7 bits, see alignment E=4.4e-39 PF17912: OB_MalK" amino acids 237 to 291 (55 residues), 52.1 bits, see alignment 2.4e-17 PF08402: TOBE_2" amino acids 284 to 357 (74 residues), 37.8 bits, see alignment E=4.2e-13 PF03459: TOBE" amino acids 304 to 356 (53 residues), 25.7 bits, see alignment 2.7e-09

Best Hits

Swiss-Prot: 52% identical to UGPC_ECO57: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Escherichia coli O157:H7

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 100% identity to ppf:Pput_1056)

Predicted SEED Role

"Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-)" (EC 3.6.3.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88P35 at UniProt or InterPro

Protein Sequence (384 amino acids)

>PP_1018 mannose/glucose ABC transporter - ATP binding subunit (Pseudomonas putida KT2440)
MATLELRNVNKTYGSGLPDTLKDIQLSIKDGEFLILVGPSGCGKSTLMNCIAGLEQITGG
AILIDEQDVSGMSPKDRDIAMVFQSYALYPTMSVRENIEFGLKIRKLPQAAIDEEVARVA
KLLQIEHLLARKPAQLSGGQQQRVAMGRALARRPKIYLFDEPLSNLDAKLRVEMRTEMKL
MHQRLKTTTVYVTHDQIEAMTLGDKVAVMKDGIIQQFGTPQQIYNDPANQFVASFIGSPP
MNFIPVRLARQDGRLLALLDSGQARCELPLGEAADALEGREIILGIRPEQIALGAADGNG
LPAIRAEVQVTEPTGPDLLVFVTLNQTKVCCRLAPDVACRVGDTLNLQFDPARVLLFDAA
NGERLHLASTGATAKDNVAHFKGR