Protein Info for PP_1006 in Pseudomonas putida KT2440

Annotation: putative outer membrane heme receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 862 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF07660: STN" amino acids 74 to 123 (50 residues), 42.6 bits, see alignment 8.5e-15 TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 132 to 858 (727 residues), 436.3 bits, see alignment E=2.2e-134 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 133 to 859 (727 residues), 542.4 bits, see alignment E=1.8e-166 PF07715: Plug" amino acids 146 to 256 (111 residues), 102.2 bits, see alignment E=4.6e-33 PF00593: TonB_dep_Rec_b-barrel" amino acids 348 to 816 (469 residues), 238.4 bits, see alignment E=5.9e-74 PF14905: OMP_b-brl_3" amino acids 529 to 826 (298 residues), 52.7 bits, see alignment E=7.5e-18

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 96% identity to ppf:Pput_1043)

Predicted SEED Role

"Iron siderophore receptor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88P47 at UniProt or InterPro

Protein Sequence (862 amino acids)

>PP_1006 putative outer membrane heme receptor (Pseudomonas putida KT2440)
MSTGPTRSSNLPRRTGQLSLLTLALLASGACSLPALAAEPAQASSPRMGDYRFSIGQQPL
VSAINAFSQVTGWQVGFSAELADGVASPGVQGSLPPDAALKRLLRGTGLSFRKISNGNVV
LERQTASNVIALQQVTVSATRSAQDVSQVPSTVSVQTREQLDRQNVNNIQDLVRYEPGVS
VSGTGQRSGLNGYNIRGIDGERILTQVDGVSIPDSFFYGPYAQTQRNYVDPEIVKRVEIL
RGPASVLYGSNAIGGAVSYFTLDPDDIIKPGKDVGARLKTGYSSADESWLTSATVAGRQG
DFDGLLHLSQRNGHETETHGSHSGDGLSRTEANPMDARTTNVLAKLGWNYADDARLGFTY
ERYKDDRDQNILSAVGGPFIPGFGGMNSYRMRQGNDTITRERFGLNHEFDLDSVVADHVK
WSFNYQIAKTDQRTDELYVASGRQVFRDRQTTYKDRQWVFDAQLDKAFSIGQTDHLFTYG
TTLKQEKVTGSRSGTGTCLNIGGTCTAIGQDSARDGQALVSDFPDPTVNTYSLFAQDEIR
WNNWTFMPGARYDYTRMEPKFTEEFLRGLESSGTAPTAQDDSDKKWHRVSPKFGLTYAFN
DNYTWYGQYAEGFRTPTAKAMYGRFQNLDQGYRVEGNPNLEPEKSKSYETGLRGNFDAGN
FDVAVFYNKYRDFIDEDAVQSANLEQTFQANNIKHATIKGAEFKGRLNLDHFGAPQGLYT
QTSIAYTYGRNDDTGQPLNSVNPLKGVFGLGYEQQNYGGLLSWTLVKRKTRVDDSTFYSP
DGSTSKFRTPGYGVLDLTGYYKVTDDVTINAGLYNLTDKKYWQWDSVRSYDGQGEAAVTQ
PANIDRLTMPGRNFGINVVWDI