Protein Info for PP_0983 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 98 to 117 (20 residues), see Phobius details amino acids 268 to 291 (24 residues), see Phobius details amino acids 298 to 316 (19 residues), see Phobius details amino acids 327 to 349 (23 residues), see Phobius details TIGR04408: LPS export ABC transporter permease LptG" amino acids 4 to 351 (348 residues), 441.1 bits, see alignment E=1.1e-136 PF03739: LptF_LptG" amino acids 6 to 351 (346 residues), 255.6 bits, see alignment E=3.7e-80

Best Hits

Swiss-Prot: 40% identical to LPTG_HAEIN: Lipopolysaccharide export system permease protein LptG (lptG) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K11720, lipopolysaccharide export system permease protein (inferred from 100% identity to ppf:Pput_1020)

Predicted SEED Role

"FIG000906: Predicted Permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88P70 at UniProt or InterPro

Protein Sequence (353 amino acids)

>PP_0983 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MAKLDRYIGQSVLLAILAVLGIILGLASLFAFIDEMGDLSDTYTVMEAGNFVLLTAPRRL
YEMLPMAALIGCLIGLGSLASSSELTIMRAAGVSIGRIVWAVMKPMLVLMLVGLLIGEYV
APVTENKAQADRSLAQGGGEAQSSKRGMWHRQGEEYVHINAVQPDGLLLGVTRYRFDSER
KIVTSSFARRAQYQNDHWLLADVRTTYFRGDHTEVVNAPEERWDVSLTPELLNTVILAPE
SLSITGLWDYIHYLSDQGLNNSRYWLAFWTKVLQPMVTAALVLMAISFIFGPLRSVTLGQ
RVFTGVLVGFVFRIGQDLLGPSSQVFGFPPLLAVVIPAGICALAGVWLLRRAG