Protein Info for PP_0879 in Pseudomonas putida KT2440

Annotation: dipeptide ABC transporter - putative ATP binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 PF00005: ABC_tran" amino acids 23 to 181 (159 residues), 108.9 bits, see alignment E=4.9e-35 PF13304: AAA_21" amino acids 148 to 216 (69 residues), 27.8 bits, see alignment E=4.1e-10 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 230 to 314 (85 residues), 70.2 bits, see alignment E=6.2e-24 PF08352: oligo_HPY" amino acids 232 to 296 (65 residues), 54.9 bits, see alignment E=1.4e-18

Best Hits

Swiss-Prot: 60% identical to DPPD_HAEIN: Dipeptide transport ATP-binding protein DppD (dppD) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K12371, dipeptide transport system ATP-binding protein (inferred from 99% identity to ppf:Pput_0918)

MetaCyc: 60% identical to dipeptide ABC transporter ATP binding subunit DppD (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88PH1 at UniProt or InterPro

Protein Sequence (322 amino acids)

>PP_0879 dipeptide ABC transporter - putative ATP binding subunit (Pseudomonas putida KT2440)
MSLLQINNLNVRFGDANAVPVVDGLDLKVDAGEILAIVGESGSGKSVTMMALMGLIDAPG
RITADSLTFDGTDMLKLSGRQRRKVVGKDIAMVFQDPMTALNPSYTVGFQIEEVLRQHLG
LKGKAARQRALELLKKVEIPAAESRLDAYPHQLSGGMSQRVAIAMAIAGEPKLLIADEPT
TALDVTIQAQIMELLVNLQKERNMALILITHDLAVVAETARRVCVMYAGQAVEVGQVPEL
FDVPAHPYSEALLAAIPEHSIGAERLATLPGIVPGRYDRPVGCLLSPRCPYVQDNCRRQR
PPLDPQAHSLVRCFYPLNQEVA