Protein Info for PP_0798 in Pseudomonas putida KT2440

Annotation: GGDEF domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details amino acids 296 to 316 (21 residues), see Phobius details PF22588: dCache_1_like" amino acids 194 to 280 (87 residues), 47.7 bits, see alignment E=1.5e-16 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 331 to 492 (162 residues), 162 bits, see alignment E=5.3e-52 PF00990: GGDEF" amino acids 334 to 490 (157 residues), 165.1 bits, see alignment E=1.2e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_0798)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88PQ0 at UniProt or InterPro

Protein Sequence (496 amino acids)

>PP_0798 GGDEF domain protein (Pseudomonas putida KT2440)
MPTQSPRFAVYRSHPELILNLGSCLAVLAIVAIVSYLLARERDSVEQSAVRSSNNIVQLI
ESDILRNVELYDQSLQGLIWAVGRKELPEVPGPIRQRLLFNEAFVDRKRGDVLWLDKQGN
IVGDSTSSVPRKANFGETGVFKAHQHNANLGLLVGPPFKAKLGDLDWCISFSRRISGPNG
EFAGLAAGALRLSYFNELFQRLDIGHDSSINLFNTDGQLLVRQPYRGQDPLIGTYYTERP
NFKRILSEQSGSFTARSHSSGKLRMFTFARVAQLPLIVLVAHSADEVFESWRRTAILVSV
ATGGLCVGILWLTLLLGRELRRRHEAEEDLAMLASTDSLTGLANRRRLDHVLRQEWARAQ
RSRKPLAILMVDVDHFKAFNQRHGHAGGDHALREVAKAIEACIRRPADLAARYGGEEFQV
VLPETDLAGAQLLAERIRANVEALAPFADDAHAVTVSIGIGLSGTQQDLGRLLGAADEAL
YRAKANGRNRVEGPLD