Protein Info for PP_0633 in Pseudomonas putida KT2440

Annotation: Type 4 fimbrial assembly protein PilC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 transmembrane" amino acids 167 to 190 (24 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 260 to 265 (6 residues), see Phobius details amino acids 375 to 396 (22 residues), see Phobius details PF00482: T2SSF" amino acids 68 to 191 (124 residues), 109.5 bits, see alignment E=5.6e-36 amino acids 272 to 394 (123 residues), 103 bits, see alignment E=5.9e-34

Best Hits

Swiss-Prot: 85% identical to PILC_PSEPU: Type 4 fimbrial assembly protein PilC (pilC) from Pseudomonas putida

KEGG orthology group: K02653, type IV pilus assembly protein PilC (inferred from 100% identity to ppu:PP_0633)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88Q63 at UniProt or InterPro

Protein Sequence (402 amino acids)

>PP_0633 Type 4 fimbrial assembly protein PilC (Pseudomonas putida KT2440)
MTSSSLLYHWHGTDANGAPVSGQTPGRSPAYVRAGLIRQGITVASLRPASGLAFSLPKRR
EKADPAGFSRQLATLLKAGVPLLQAFEVMGRSGCDAAQAALLERLKQDVASGLGLADALQ
RHPAWFDALYCNLVRVGEQSGTLDRQLEQLAGMLEQRRVLHKKVRKAMIYPLLLLLTGLG
VSAILLLEVIPKFESMFSGMGAALPAFTQWVINLSTGLSRFAPLLLVMGVVMGVAVRQLY
RQHAPARLWISRRVLGLPVFGKLLGQAALARFARSLATSYGAGVPLLDALGTVARVTGGD
LHEQAVLRLRQGMANGQGLNQAMAGEPLFPPLLVQLTAIGESSGTLDQMLEKAASHYEEQ
VSQALDQLTSLLEPAIVLILGLLVGGLVVAMYLPIFQLGSLI