Protein Info for PP_0487 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 transmembrane" amino acids 15 to 53 (39 residues), see Phobius details amino acids 84 to 107 (24 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 147 to 181 (35 residues), see Phobius details amino acids 201 to 227 (27 residues), see Phobius details amino acids 243 to 264 (22 residues), see Phobius details PF01925: TauE" amino acids 24 to 256 (233 residues), 146.6 bits, see alignment E=4.9e-47

Best Hits

KEGG orthology group: K07090, (no description) (inferred from 100% identity to ppu:PP_0487)

Predicted SEED Role

"Putative membrane protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88QK3 at UniProt or InterPro

Protein Sequence (265 amino acids)

>PP_0487 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MDIAMEMLGSYWAEHWLLAVLILGAIAFVAGFVDSIAGGGGLFLVPGFLLVGMPPQVALG
QEKLVSTLGTLAAIRNFLANSKMVWQVALVGVPFSLLGAYLGAHLIVSISQETVGKIILA
LIPLGILIFLTPKDRPVEERELSSRMLFTVVPLTCLAIGFYDGFFGPGTGSMFIIAFHYL
LRMDLVSSSANSKTFNFASNIGALVAFVSAGKVVYLLALPLVACNILGNHLGSSLALRKG
NDVVRKALVFSMLCLFTSLGVKYLT