Protein Info for PP_0351 in Pseudomonas putida KT2440

Annotation: putative Transmembrane sensor protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 transmembrane" amino acids 83 to 102 (20 residues), see Phobius details PF16220: DUF4880" amino acids 12 to 51 (40 residues), 40.9 bits, see alignment 1.5e-14 PF04773: FecR" amino acids 114 to 204 (91 residues), 66.1 bits, see alignment E=3.3e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_0351)

Predicted SEED Role

"Transmembrane sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88QY3 at UniProt or InterPro

Protein Sequence (318 amino acids)

>PP_0351 putative Transmembrane sensor protein (Pseudomonas putida KT2440)
MSNLPVSSRVLEAAIAWKLSLGESSGTPDERNEFMRWHAASEEHARAWRQLGAMDQRVSA
AAGPARQALLQSRASLRRRIGKVGGGLAGTFLLGALLAWVGAPSLAPSYWLADQRTATGE
LRTLRLEDGTLLSLNTHTAVDIEYAGAQRVIVLHQGEISVETGHQDPRPLLVRTEDGRLR
PLGTRFLVRREAGGTRLEVLQASVAAMPHDSGDEQVLREGQQVLMNANGLGEVGTVPAGA
DAWTRGMLVVDNVRLGDLLATLGQYRSGYLGVDAKVADLRVTGSFPLTNTDLALASLVPA
LPVKIERHTQWWVNVTSK