Protein Info for PP_0008 in Pseudomonas putida KT2440

Annotation: ribonuclease P protein component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00825: Ribonuclease_P
  • amino acids 6 to 113 (108 residues), 109.3 bits, E=5e-36
• TIGR00188: ribonuclease P protein component
  • amino acids 11 to 115 (105 residues), 88 bits, E=2.4e-29

Best Hits

Swiss-Prot: 100% identical to RNPA_PSEP1: Ribonuclease P protein component (rnpA) from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)

KEGG orthology group: K03536, ribonuclease P protein component [EC: 3.1.26.5] (inferred from 98% identity to ppg:PputGB1_0001)

MetaCyc: 47% identical to RNase P protein component (Escherichia coli K-12 substr. MG1655)
Ribonuclease P. [EC: 3.1.26.5]; 3.1.26.5 [EC: 3.1.26.5]

Predicted SEED Role

"Ribonuclease P protein component (EC 3.1.26.5)" in subsystem tRNA processing (EC 3.1.26.5)

MetaCyc Pathways

• tRNA processing (10/10 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.5

Sequence Analysis Tools

See P0A167 at UniProt or InterPro

Protein Sequence (134 amino acids)

>PP_0008 ribonuclease P protein component (Pseudomonas putida KT2440)
MVSQDFSREKRLLTPRHFKAVFDSPTGKVPGKNLLILARENGLDHPRLGLVIGKKSVKLA
VQRNRLKRLMRDSFRLNQQLLAGLDIVIVARKGLGEIENPELHQHFGKLWKRLARSRPTP
AVTANSAGVDSQDA