Protein Info for PFR28_04768 in Pseudomonas sp. RS175

Annotation: Fructose dehydrogenase large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 739 PF01494: FAD_binding_3" amino acids 6 to 36 (31 residues), 22.9 bits, see alignment (E = 1.5e-08) PF13450: NAD_binding_8" amino acids 10 to 40 (31 residues), 27.5 bits, see alignment (E = 9.3e-10) PF00732: GMC_oxred_N" amino acids 240 to 351 (112 residues), 28 bits, see alignment E=5.7e-10 PF05199: GMC_oxred_C" amino acids 481 to 601 (121 residues), 71.9 bits, see alignment E=2.6e-23

Best Hits

KEGG orthology group: None (inferred from 84% identity to pba:PSEBR_a188)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (739 amino acids)

>PFR28_04768 Fructose dehydrogenase large subunit (Pseudomonas sp. RS175)
MTIEQAEVVIVGAGLAGSIVAYQLAMAGVEVLVLESGPEIPANRTQYLERFYTTTLKTPE
SPYPPVTTLDPPRNPAGQNAPRATIADLILGWDKPEVSYLVQKGPMPFTSTYERVGGGTT
WHWVGTCLRMVPNDFRLRSLYNVGVDWPIGYDDLQSAYCRAEAEIGVSANVADQAYLGMT
FPEGYEFPMHSIPLSLVDGSFVAAVTGQTFDGLPLVVSPTPAGRNSQPYAGRRVCAGNTN
CTPICPIQAKYDATVTMNKALATGKVKVLYRTVATKLNVGLDGTIFGVEFKQYQLGDGPM
TGFGEAIAQRYVIAAHAIETPKLLLNSVTPAWPKGVANSSGQVGRNLADHPIYLAWGLMP
EGKAIFPYRGPLSTAGIESLRDGAFRSERAAWRIEIGNEGWNWPANDPYDTVADFIDGTN
NNGVNPVKSDQDSKAATEALYGTALVQKLNDIFVRQFRIAFLVEQVEDDPDNAKCYIVPS
AGYKDLLGIPRPEIHYELSKYTQKGFLEAKRLATHIIKDLLGAVELTKPLTPGTFTYGNE
PMSFQGAGHLMGTYRMGSDPATSVVDKDQRSWDHKNLFLVGDGVFPSSGTSNPSLTIAAL
SFLAADTVANDLKAVTMQVQSNVAWQGTGVQVNGLVPRLVRYVSGLWCASPQGGNVDGKG
GSRHIDYSSYALPGAAEGALIGRVGNGGAPFLVGDLAQVPGNQQGELQLCINDDLTGQHG
AGLSDNTGALTIRVEFGAL