Protein Info for PFR28_04131 in Pseudomonas sp. RS175

Annotation: Sarcosine oxidase subunit gamma

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04268: SoxG
  • amino acids 53 to 203 (151 residues), 272.7 bits, E=9.5e-86
• TIGR01375: sarcosine oxidase, gamma subunit family
  • amino acids 53 to 203 (151 residues), 172.7 bits, E=2.4e-55
• PF01571: GCV_T
  • amino acids 84 to 206 (123 residues), 40.2 bits, E=2.5e-14

Best Hits

KEGG orthology group: K00305, sarcosine oxidase, subunit gamma [EC: 1.5.3.1] (inferred from 98% identity to pba:PSEBR_a5211)

Predicted SEED Role

"Sarcosine oxidase gamma subunit (EC 1.5.3.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.5.3.1)

MetaCyc Pathways

• glycine betaine degradation I (6/8 steps found)
• creatinine degradation I (2/4 steps found)
• creatinine degradation II (1/5 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.5.3.1

Use Curated BLAST to search for 1.5.3.1

Protein Sequence (210 amino acids)

>PFR28_04131 Sarcosine oxidase subunit gamma (Pseudomonas sp. RS175)
MTAVNVYQQRPTTGAKAESSLHHADLASLVGKGRKNAGVTVREKKLLGHLTIRGDGHDPA
FAAGVHKALGLELPGALTVIVKGETSLQWLGPDEWLLVVPTGEEFAAEQKLREALGDLHI
QIVNVSGGQQILELSGPNVRDVLMKSTSYDVHPSNFPVGKAVGTVFAKSQLVIRHTAEDT
WELVIRRSFSDYWWLWLQDASAEYGLSVQA