Protein Info for PFR28_02876 in Pseudomonas sp. RS175

Annotation: Formylglycine-generating enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF03781: FGE-sulfatase" amino acids 44 to 296 (253 residues), 194.8 bits, see alignment E=1.1e-61

Best Hits

KEGG orthology group: None (inferred from 88% identity to pba:PSEBR_a3914)

MetaCyc: 66% identical to dihydropyoverdine dehydrogenase (Pseudomonas aeruginosa PAO1)
RXN-20771

Predicted SEED Role

"PvdO, pyoverdine responsive serine/threonine kinase (predicted by OlgaV)" in subsystem Siderophore Pyoverdine

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>PFR28_02876 Formylglycine-generating enzyme (Pseudomonas sp. RS175)
MNRELHSFSVKTLPALALAAATGLLCIGAQAAQPGQVFRDCKDCPQMVVLPSGTFTMGTP
DDEVGREPDEGPMHPVTFARPVAISRFQVLKGEWFAYLQDTGYTMPDADKRPGRACKAGV
PDYQGSDPGKQYTDMHPAVCMNFEEANAYVAWLSKKTGKQYRLVSESLREYAARGGSTGP
FPFPFDDGKDYSIAQHANTYGAADGYNFTSPAGRFAPNAFGVYDMHGNVYEWTADCYNPD
YVGAPSDGSAWLSGDCKVRRIRGNDWGEAPVFSRSGNRNAVYPDARGDWLGFRVARDM