Protein Info for PFR28_01050 in Pseudomonas sp. RS175

Annotation: Serine/threonine-protein kinase PknD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 transmembrane" amino acids 441 to 457 (17 residues), see Phobius details amino acids 534 to 554 (21 residues), see Phobius details PF13672: PP2C_2" amino acids 13 to 183 (171 residues), 36.3 bits, see alignment E=9.1e-13 PF00069: Pkinase" amino acids 264 to 460 (197 residues), 98.2 bits, see alignment E=1.2e-31 PF07714: PK_Tyr_Ser-Thr" amino acids 278 to 501 (224 residues), 46.2 bits, see alignment E=7.4e-16

Best Hits

KEGG orthology group: None (inferred from 96% identity to pba:PSEBR_a1689)

Predicted SEED Role

"Serine/threonine protein kinase (EC 2.7.11.1)" (EC 2.7.11.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (556 amino acids)

>PFR28_01050 Serine/threonine-protein kinase PknD (Pseudomonas sp. RS175)
MSLQLSFAEASAIGPREENQDALRLVTPAPALAASKGYLFAIADGVSQCADGGLAARSTL
QALALDYYATPQTWGVAQALDRLLLAQNRWLQANGGGQPLLTTVSALVLRGRRFTLAHVG
DCRVYRWHADQLQRVSEDHVWEQQGMQHVLKRALGLDQHLILDFLDGELRTDETFVLLSD
GVWAVLGDTAIAGILRDQPDLDLAAQTLVNAAHLAGSQDNASALLVRVDALGEASIGDAL
IQLQQWPLPPALKPGQVFEGWRIEGLLGQSQQSLLYRVHDSQGQPWLLKTLPGHLRDDTR
AGQALLSEEWFLRRVAGRQFPEVHGVAQRQHLYYVMREYPGITLAELFDRGGTLPLARWQ
DLAQRLVRAVGLLHRRQIYHRDIKPENLHLGDDGELRLLDFGLAYCPGLSEDQANVLPGT
PSYIAPEAFGGIAPTAQQDLYAVGVTLYFLLTGHYPYGEIEAFQRPRFGMPVSANRYRPD
LPEWLGQSLERAVAADPGQRFETAEEWLLLLEQGERRSLSVRPRPLLEREPLKVWRTLAL
VSLVVNVVLLFLVFHS