Protein Info for PFLU_RS23110 in Pseudomonas fluorescens SBW25

Annotation: XdhC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 transmembrane" amino acids 245 to 258 (14 residues), see Phobius details PF02625: XdhC_CoxI" amino acids 15 to 84 (70 residues), 71.4 bits, see alignment E=4.8e-24 PF13478: XdhC_C" amino acids 167 to 308 (142 residues), 127.7 bits, see alignment E=3.8e-41

Best Hits

KEGG orthology group: K07402, xanthine dehydrogenase accessory factor (inferred from 100% identity to pfs:PFLU4716)

Predicted SEED Role

"Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K0P5 at UniProt or InterPro

Protein Sequence (328 amino acids)

>PFLU_RS23110 XdhC family protein (Pseudomonas fluorescens SBW25)
MDSVDLNVLRSVLEWRRAGQQVVLYSVVQTWGSAPRPPGAMLALRGDGVVIGSVSGGCIE
DDLIARLQDGRLPADGPPVQLVTYGVTRDEAARFGLPCGGTLRLTEERVGDWAWVSELLA
RCEDHQVVARELDLASGDVTLSSASKTDAVTFDGERLRAIYGPRWRLLLIGAGQLSRYVA
EMARLLDFEVLICDPRDEFVYGWEEQHGRFVPGMPDEAVLNIQTDERTAIVCLTHDPRLD
DMALLTALNSSAFYIGALGSRVNSQKRRENLAALGLSAEAIARLHGPIGLHIGSHTPSEI
ALSLMAEIVAIKNGVAPMQKKPLPVVAQ