Protein Info for PFLU_RS03135 in Pseudomonas fluorescens SBW25

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 912 TIGR00229: PAS domain S-box protein" amino acids 425 to 547 (123 residues), 29.3 bits, see alignment E=3.9e-11 PF08447: PAS_3" amino acids 452 to 533 (82 residues), 49.6 bits, see alignment E=9.5e-17 PF08448: PAS_4" amino acids 560 to 669 (110 residues), 23.5 bits, see alignment E=1.4e-08 PF00512: HisKA" amino acids 683 to 749 (67 residues), 29.5 bits, see alignment 1.6e-10 PF02518: HATPase_c" amino acids 795 to 908 (114 residues), 73.2 bits, see alignment E=5.8e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU0637)

Predicted SEED Role

"Sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K7F1 at UniProt or InterPro

Protein Sequence (912 amino acids)

>PFLU_RS03135 PAS domain-containing sensor histidine kinase (Pseudomonas fluorescens SBW25)
MTSGDNLFGRLLGRTGAPPLDTPGVSVPGLHLQLDPQGHVLSISGTLRPQLATPGMGETP
PLLRELLCAGSALSVEGRPADWQHQSLDLDFQSTTGQVLHTRGWVEPEGDGWSLRLLDVG
DLLADRQLAQHREQNHQLISRMSEQLQLCSLSRLPEVFNEHLRNLAQHWQIPCVALALFD
AEDQGWRIYSHYTAHDAPALWQTGQHLGTLLDSANGSAPLSLAQARREHPSLNGIFGNAD
GFLVPYRDSQGVAAWLLCGLYNGQQHTRDREWLNLTAALAAPLLSRLREQRDHQQLDRMD
ALQGLLGTGWWELLPATQEIQLAPQLQHSLSLEDGPTRQALGVWLEQIHPADRQALTSRL
HDLQTLDKPLLTSVRLQRTDTEHNPLWYRLQGHVLGMGDQRRWVGFMLDISDIKNQQLQA
AAAHARLDNLIASSPAVIYVQRYVSGALHPAFFSDSLLPLLGWTLDDCNHDSLASLIHPE
DRDLYFERTRRLLREGAVRSRYRLRDKQGHYHWLLDEAKLLRDDLGLPLEAVGLWLDVTE
ATLAAEQIKQSEERYRILVEDSPAMICRYRPDLTLTFGNTPLANYLECLPAQLPGLNLGH
WLSDEQRQAFVQRISQLTPEFPVSTAEISLELPGREHAWWVWSDRGVFDEQGVLVEVQAV
GRDNTEVRRSQQQLTQSAKMATLGEMATGLAHEINQPLNVMRMAIVNVLKRLGNGDAQTD
YLTEKLQRIDAQVQRAARVVDHMRVFGRRSEIEQQPFDPSQAVEGTLSLLGEGLRGKGVD
VRVTPADFTVQVKGHVDQLEQVLINLMVNARDALLSKHEKDPAFRPWIALHCEHDSRHVR
LWVEDNGGGIDPRLIERIFEPFFTTKPIGVGTGLGLSVSYGIVENMGGRLSVVNGPAGAR
FCVELPVDQITR