Protein Info for PFLU_RS02940 in Pseudomonas fluorescens SBW25

Annotation: TonB-dependent copper receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF07715: Plug" amino acids 48 to 150 (103 residues), 52.5 bits, see alignment E=6.3e-18 TIGR01778: TonB-dependent copper receptor" amino acids 51 to 686 (636 residues), 962.9 bits, see alignment E=4.9e-294 PF00593: TonB_dep_Rec" amino acids 204 to 644 (441 residues), 168.7 bits, see alignment E=4.3e-53

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to pfs:PFLU0595)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K5W6 at UniProt or InterPro

Protein Sequence (686 amino acids)

>PFLU_RS02940 TonB-dependent copper receptor (Pseudomonas fluorescens SBW25)
MSRFSADTRLGCTPVLAALCGALLAPQVHADEHELSPTVITAIAPSSPLTVITNPKDPRQ
PVPASDGGDYLKTIPGFALVRNGGTNGDPVLRGMFGSRLNILTNGSMMLGACPGRMDAPT
SYISPETYDKLTVIKGPQTVLWGPGASAGTVLFEREPEQFGELGTRLNASVLAGSNGRFD
KVIDAAAGGPLGYVRVIGNQAHADDYKDGNNDTVASRYDKWNSDVAVGFTPDADTLLELT
AGRGDGEARYAGRGMDGSQFLRESLGLRFEKSNIGDVLDKVEAQVYYNYADHVMDNYSLR
TPSGTGMMAGPMASNVDRRTLGARIKATWRWADVQLISGLDAQTNEHRQRSSMGIDTYKD
LPKVKDANFHNYGVFGELTWYAADRDRLITGARLDRASAKDFRQTTGSGMSARTNPTADA
TRADTLPSGFTRYEHDLADSPTTLYAGLGHSERFPDYWELFSPNTGAVGSVNAFDGVKPE
KTTQLDFGAQYKAEALEAWASGYIGRVQDFILFDYRPGMMGTTSQARNVDARIMGGELGT
AYKLTRNWKADATLAYAWGKNSSDGKALPQMPPLDARLGLTYSEDDWSAGALWRVVAAQN
RIDQNKGNVVGKDFDKSGGFGVFSLNAAYRLNKHFKVSTGVDNLFGKAYAEHLNLAGNAG
FGYPASDPQAIKESGRTLWTKVDMSF