Protein Info for PFLU_RS01175 in Pseudomonas fluorescens SBW25

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 PF00005: ABC_tran" amino acids 48 to 196 (149 residues), 127.4 bits, see alignment E=9.8e-41 PF09383: NIL" amino acids 295 to 353 (59 residues), 47.3 bits, see alignment E=2.3e-16

Best Hits

Swiss-Prot: 86% identical to METN2_PSEPF: Methionine import ATP-binding protein MetN 2 (metN2) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 100% identity to pfs:PFLU0238)

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KDK0 at UniProt or InterPro

Protein Sequence (371 amino acids)

>PFLU_RS01175 ATP-binding cassette domain-containing protein (Pseudomonas fluorescens SBW25)
MTAAHSQLRDLGLPPRDAEQTELHPDLNRAHVRFINLGKTYDGTVHALQGIDLAIQRGEV
FGIIGRSGAGKSSLIRTINRLEQPSSGRVLIDQVDIGDFDEDRLVALRRRIGMIFQHFNL
MSAKTVWQNVELPLKVAGVPKPQREKKVRELLELVGLQDKHTSYPAQLSGGQKQRVGIAR
SLVHDPQILLCDEATSALDPETTQSILGLLREINQRLGLTIVLITHEMAVIRDICDRVVV
LEHGRIVEQGPVWEVFGNPQHEVSKTLLAPLQHGLPDELQSRLQAKPATADASVVLRLRF
TGSDTDEPDLAALFSALGGRVRLLQGGVERIQGHALGQLLLAVKGSPHSAEELRNRAGNW
AQQVEVLGYVV