Protein Info for OKGIIK_01875 in Rhodanobacter sp. FW510-T8

Name: tolB
Annotation: Tol-Pal system beta propeller repeat protein TolB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR02800: Tol-Pal system beta propeller repeat protein TolB" amino acids 23 to 438 (416 residues), 491.8 bits, see alignment E=8.8e-152 PF04052: TolB_N" amino acids 32 to 136 (105 residues), 104.4 bits, see alignment E=8.5e-34 PF07676: PD40" amino acids 214 to 237 (24 residues), 33 bits, see alignment (E = 1.1e-11) amino acids 253 to 273 (21 residues), 22.3 bits, see alignment (E = 2.5e-08) amino acids 291 to 326 (36 residues), 52.3 bits, see alignment 9.5e-18

Best Hits

Swiss-Prot: 49% identical to TOLB_METCA: Tol-Pal system protein TolB (tolB) from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

Predicted SEED Role

"tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>OKGIIK_01875 Tol-Pal system beta propeller repeat protein TolB (Rhodanobacter sp. FW510-T8)
MIKTMRKFSSSLVVILLAAVALFAGPATAQSLNVDIVGGVKTATPIVVVPFAQAGGAPLS
TDVADVMRNDFNRSGKFRSLAKSDIVEFPSKGSDIKFATWRLLKQDYIVVGNITDAGNGM
VQVEYELWDVNKQQSLLHQQMPPAPAGDLRGVAHQIADIIYEKITGVRGAFWTRIAYITA
VGLGNHTTYSLIVADSDGYNPQVVARSKESLLTPAWSPDGRKLAYVSFESGNSSIYVQDI
TTGSRQLVESHPRGINGAPAWSPDGSKLAVALSYVGNLELFVLDLASRHETRLTNSLSID
TEPVWAPDGKSIFFTSDRSGRPQIYQVPASGGTPQRISFQGQSNLNADVSYDGKQIAMVQ
GNGNVYRIAIMDRSLGDQVRFLSPGPIDESPSFAPNASMLLYAATEGRRGVLYAVSADGM
VRQRLVLSDGDVREPAWGPYRQR