Protein Info for OH686_23735 in Pseudomonas sp. S08-1

Annotation: Putative SigmaB asociated two-component system sensor protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 587 PF00512: HisKA" amino acids 222 to 290 (69 residues), 52 bits, see alignment E=1.2e-17 PF02518: HATPase_c" amino acids 338 to 444 (107 residues), 85.9 bits, see alignment E=5.2e-28 PF00072: Response_reg" amino acids 466 to 564 (99 residues), 38.3 bits, see alignment E=2.8e-13

Best Hits

Predicted SEED Role

"Putative SigmaB asociated two-component system sensor protein" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (587 amino acids)

>OH686_23735 Putative SigmaB asociated two-component system sensor protein (Pseudomonas sp. S08-1)
MHKVRRIVSIDIREEVDVVTCRQSAKRIAAWLDLSQLEQIRFATSVSELARNIYQYAGQG
EFLFELVENKAGLLCGLRFIADDQGPGIVAIDSILDGSYVSPTGMGVGLRGAQRLMDEFE
IQTSADGTRILGMKAIHPPRPSPSPTQLREIREQLHSDGVADPYIELQVRGKELLLTAAE
LQNKQFELEATNQELENTNKGVVALYSELEKATDELRTASQSKSRFFANMTHEIRTPINI
VENISKILLKGVDGPLNPEQYKQVAFIRDAACELSELVNELLDLSEAESGRIEITPVRFT
LADFVEQLRQFTGALAQRYPALAWEVLGATHDVVLETDRHRLFQILRNLIGNAFKYTPSG
KVSVRTYLPDEQNVEFLVEDTGIGIDAENHSRVFEEFLRVRNPAAPQIQGTGLGLPVAQR
LARLLRGEISLDSELGRGSRFLLQVARLYDQQAPEPAALDLNGINILLIDDSEADRYLLS
RLLQPYHPVIIEAVSATSSIDKLHAVRPDIIFLDLDLPDISGEDLLESMDWSMHSRVLIN
TSKPLAGAALEHLQRHSRAVLHKSHPDYAEQVLHHVGRLVEEQRDAH