Protein Info for OH686_21825 in Pseudomonas sp. S08-1

Annotation: lipid kinase YegS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 TIGR03702: lipid kinase YegS" amino acids 5 to 296 (292 residues), 435.1 bits, see alignment E=1.1e-134 PF00781: DAGK_cat" amino acids 6 to 125 (120 residues), 88.5 bits, see alignment E=2.7e-29 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family" amino acids 7 to 290 (284 residues), 189.3 bits, see alignment E=7.5e-60 PF19279: YegS_C" amino acids 145 to 287 (143 residues), 42.1 bits, see alignment E=8e-15

Best Hits

Swiss-Prot: 75% identical to YEGS_PSEAE: Probable lipid kinase YegS-like (PA3023) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K07029, (no description) (inferred from 79% identity to pfv:Psefu_2926)

Predicted SEED Role

"Transcription regulator [contains diacylglycerol kinase catalytic domain]"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>OH686_21825 lipid kinase YegS (Pseudomonas sp. S08-1)
MSERKALLILHGKQAQNEEVRAAVMALRENGWELAVRLTWEGGDAARLVDEALAAGYPTL
IAGGGDGTLREVAEAMALAGSDASLALLPLGTANDFCRAAGIPLPPAEALSLLEFEPRSI
DLGEVDGQLFLNMATGGFGSKVTANTSEELKKMLGGAAYFLTGLTRFPEVHAAFGRFSGP
GFTWEGDFLALGIGNGRQAGGGHVMCPQARIDDGLLDICIVPAPQDVVGTLGTLLSGGIL
GLESVSISARLPWLEVEAPEGLDINLDGEPLESHRLRFAARTGALRLHLPNISPLLQDR