Protein Info for OH686_10555 in Pseudomonas sp. S08-1

Annotation: Phosphoethanolamine transferase EptC [E.coli], specific for LPS heptose I residue

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 587 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 46 to 65 (20 residues), see Phobius details amino acids 72 to 93 (22 residues), see Phobius details amino acids 121 to 141 (21 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details PF00884: Sulfatase" amino acids 239 to 526 (288 residues), 189.3 bits, see alignment E=5.1e-60

Best Hits

Swiss-Prot: 54% identical to CPTA_SALTY: Phosphoethanolamine transferase CptA (cptA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 75% identity to avn:Avin_04430)

MetaCyc: 53% identical to phosphoethanolamine transferase EptC (Escherichia coli K-12 substr. MG1655)
2.7.8.M9 [EC: 2.7.8.M9]

Predicted SEED Role

"UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide" in subsystem Lipid A modifications

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (587 amino acids)

>OH686_10555 Phosphoethanolamine transferase EptC [E.coli], specific for LPS heptose I residue (Pseudomonas sp. S08-1)
MTIAQRADASRGGIDWAGLGWTFLFFWYFSGVTQVLIYASDSAGFSGLRQSLVLSLLWLV
PLVLFPARARLLAALIGVPLWLCSLAGFGYFLIYGQEFSQSVIFILFESNVSEGTEYLAQ
YFAWWMVPAFLAYGLGAWLLWRKVRPVYLSRPGALLASLFLLFSSLGYPALRQFSKHDDL
RSALENFEERIEPATPWQLVVGYRQYRAQLANMQALLEGRQRIAPLTDLVDAHAGQPATL
VLVIGESTNRQRMSLYGYDRQTTPELDKLRDQLQVFGNVVTPRPYTIEALQQVLTFADQN
NPDAYLNTPSLVSVMKQAGYKTYWITNQQTITKRNTMLTTFSKQADEQFYLNNNREQNAR
QYDGDVLEPFAKVLDEDAPRKFIVVHLLGTHMSYQYRYPPEYERFTDRQGAPEHVSDAQL
PTYNAYDNAVLYNDFVVSSLIKRFSATDPNGFLLYLSDHGEAVFDAPKAEVLGRNEAAPT
GPMYTIPFILWNSPKWQAQQPRDFSQAFGRAASSSSLVHTWADLAGLDFAERDRSRSLVG
ADFKPRPLLIGNPQQPQNLIDFSLIKPKAVDHELARQEPHKVSAQPL