Protein Info for NOLOHH_23070 in Escherichia coli ECOR27

Name: int
Annotation: Integrase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 PF09003: Arm-DNA-bind_1" amino acids 1 to 69 (69 residues), 111.7 bits, see alignment E=2e-36 PF02899: Phage_int_SAM_1" amino acids 81 to 158 (78 residues), 34.6 bits, see alignment E=2.9e-12 PF00589: Phage_integrase" amino acids 179 to 345 (167 residues), 133.9 bits, see alignment E=7.9e-43

Best Hits

Swiss-Prot: 98% identical to VINT_BP434: Integrase (int) from Enterobacteria phage 434

KEGG orthology group: None (inferred from 98% identity to eoj:ECO26_0827)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>NOLOHH_23070 Integrase (Escherichia coli ECOR27)
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHK
RKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDVPLEDIT
TKEIAAMLNGYIDDGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRL
TADEYLKIYQSAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKI
AIPTALHVDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSF
EGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK