Protein Info for NOLOHH_18890 in Escherichia coli ECOR27

Name: safA
Annotation: two-component system connector SafA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 65 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details PF17073: SafA" amino acids 1 to 65 (65 residues), 160.2 bits, see alignment E=4.8e-52

Best Hits

Swiss-Prot: 100% identical to SAFA_ECOL6: Two-component-system connector protein SafA (safA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 97% identity to eco:b1500)

Predicted SEED Role

"FIG00638899: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (65 amino acids)

>NOLOHH_18890 two-component system connector SafA (Escherichia coli ECOR27)
MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFII
NSLQD