Protein Info for NOLOHH_00305 in Escherichia coli ECOR27
Name: virB9
Annotation: P-type conjugative transfer protein VirB9
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K03204, type IV secretion system protein VirB9 (inferred from 54% identity to yps:pYptb0013)Predicted SEED Role
"Forms the bulk of type IV secretion complex that spans outer membrane and periplasm (VirB9)" in subsystem Type 4 secretion and conjugative transfer
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (302 amino acids)
>NOLOHH_00305 P-type conjugative transfer protein VirB9 (Escherichia coli ECOR27) MNRVAFIGGLLLFSAQVNSAVTPQGSRYDSRMQTVSYNAANTTVITAGVGYLSTLLFDDE ETVLDARPGMEKGWNIQKDANRVYIRAVPVTQPVMDEEGKQVSQVFEPNAKDWPTNLFVV TTKRYYSIDLRVVDASAPQDKVSYVVSYRYPQDEREKSSRMELARLQELKQQQENKRIAK ALDDAQAPRNWLFSMSIGKDSNMIKPDFAYDDGRFTYIGFSPIKKIPAVMLYSNGKEIAT SPGIKQIGNFKTLVVDKTNPAFVLRYGNAVIGLVNQGYGKVTVKDGSTVSPDVERVEVND GK