Protein Info for NOLOHH_00295 in Escherichia coli ECOR27

Name: virB11
Annotation: P-type DNA transfer ATPase VirB11

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 TIGR02788: P-type DNA transfer ATPase VirB11" amino acids 19 to 327 (309 residues), 318.8 bits, see alignment E=1.6e-99 PF00437: T2SSE" amino acids 22 to 283 (262 residues), 124.1 bits, see alignment E=3e-40

Best Hits

KEGG orthology group: K03196, type IV secretion system protein VirB11 (inferred from 62% identity to yps:pYptb0015)

Predicted SEED Role

"ATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB11)" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (344 amino acids)

>NOLOHH_00295 P-type DNA transfer ATPase VirB11 (Escherichia coli ECOR27)
MTDNNISLNYIRDTYFGAFLKTEGLTEVAVNRPNEVFTKIYGKWERHEVDFSLDVAQKFA
RQLATYHKDNISDVKPILSATLPTGERGQVVLPPASESNTVSITLRKPSSVQIPHQTYID
NGFYDRIAGKEKGNSRNDELLRLYKNKLFPEFMEKCIEYGKTMVFVGETGSGKTTYLKTL
IDYIPLHLRIVTIEDNPEVKFYRHQNYVHLFYPSEAGNSDKAIITPASLIRANYRMNPDR
ILITEVRGGEAWDFLKIVSSGHEGAITSLHAGSPYEAIMGLVERCYQNTECSRLPYSVLL
SKVLSSIDVIASIKLEGDVRRIGEIYYKDADLESYRKRFRDENF