Protein Info for MPMX26_03125 in Acinetobacter radioresistens SK82

Annotation: Thiol:disulfide interchange protein DsbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01323: DSBA" amino acids 62 to 186 (125 residues), 55.7 bits, see alignment E=2.9e-19

Best Hits

Swiss-Prot: 38% identical to DSBA_PSESM: Thiol:disulfide interchange protein DsbA (dsbA) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

KEGG orthology group: K03673, thiol:disulfide interchange protein DsbA (inferred from 69% identity to aci:ACIAD0045)

Predicted SEED Role

"Periplasmic thiol:disulfide interchange protein DsbA" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (204 amino acids)

>MPMX26_03125 Thiol:disulfide interchange protein DsbA (Acinetobacter radioresistens SK82)
MKKFLLGAVAASVLAFSGNAMANFVAGQDYQVVAKPVKVEKPGRIEVREFFWYGCGHCFA
LEPHMQGWLKKLPKDVRFVRTPAAMNPLWEQAARAYYVSEALGVRQKAHLQLFHDIHDKQ
RPILEQAQLAKFYTRYGIPEAKFNSTYKSFPITSKIAQAKNLAAQYQLSGVPAVTVNGKY
IVQGNDAKVIQVVNYLIEKERKAK