Protein Info for MPMX26_02949 in Acinetobacter radioresistens SK82

Annotation: Disulfide bond formation protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 174 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 40 to 58 (19 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 141 to 161 (21 residues), see Phobius details PF02600: DsbB" amino acids 7 to 158 (152 residues), 148.2 bits, see alignment E=1.2e-47

Best Hits

Swiss-Prot: 74% identical to DSBB_ACIBT: Disulfide bond formation protein B (dsbB) from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)

KEGG orthology group: K03611, disulfide bond formation protein DsbB (inferred from 75% identity to abc:ACICU_03564)

Predicted SEED Role

"Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (174 amino acids)

>MPMX26_02949 Disulfide bond formation protein B (Acinetobacter radioresistens SK82)
MQWGSYRFVNGLLLIASIVGMAFALYLEHVKGLEPCPLCVFQRIGLIAMGLVASVSVIHN
PVSNIVKRLYAFLATLAMIWSVGVAARHVWLQHLPPDQVPSCGPGLDYLVDALPLKTVFQ
QVLTGSGECAMVDWTFLGQSLPFWSLVFFCILLMLCLWQLVRNYPYSKAVKKKY