Protein Info for MPMX26_02740 in Acinetobacter radioresistens SK82

Annotation: Intermembrane phospholipid transport system permease protein MlaE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 49 to 75 (27 residues), see Phobius details amino acids 84 to 111 (28 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details amino acids 236 to 256 (21 residues), see Phobius details TIGR00056: ABC transport permease subunit" amino acids 5 to 256 (252 residues), 286.6 bits, see alignment E=1.1e-89 PF02405: MlaE" amino acids 41 to 252 (212 residues), 244.4 bits, see alignment E=4.9e-77

Best Hits

Swiss-Prot: 65% identical to MLAE_HAEIN: Intermembrane phospholipid transport system permease protein MlaE (mlaE) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 89% identity to aci:ACIAD3243)

Predicted SEED Role

"Uncharacterized ABC transporter, permease component YrbE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>MPMX26_02740 Intermembrane phospholipid transport system permease protein MlaE (Acinetobacter radioresistens SK82)
MNAVAWLGRLVIERVRGIGVATLMLLQIIFSLPTWLGVKLFIYQMYRVGVMSLLIITVSG
LFIGLVLGLQGYSILVNVGSEAMLGTMVALTLLRELAPVVAALLFAGRAGSALTAEIGLM
KATEQLSSMEMIGVDPLKRIVSPRLWAGIVSLPMLTVIFGAVGILGGKLVGVDFLGVDEG
SFWSGMQSSVQFGHDVVNGIIKSTVFALICTWIAVYQGYACEPTSEGIATSTTRTVVFSS
LCVLGFDFVLTAVMFGGV