Protein Info for MPMX26_02402 in Acinetobacter radioresistens SK82

Annotation: Nuclease SbcCD subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF00149: Metallophos" amino acids 13 to 244 (232 residues), 58.1 bits, see alignment E=1.7e-19 TIGR00619: exonuclease SbcCD, D subunit" amino acids 13 to 270 (258 residues), 183.3 bits, see alignment E=3.5e-58 PF12320: SbcD_C" amino acids 296 to 397 (102 residues), 45 bits, see alignment E=1.2e-15

Best Hits

KEGG orthology group: K03547, exonuclease SbcD (inferred from 70% identity to aci:ACIAD0917)

Predicted SEED Role

"Exonuclease SbcD" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>MPMX26_02402 Nuclease SbcCD subunit D (Acinetobacter radioresistens SK82)
MVALGFGAGMAVRFFHTSDWHLGQFFYNHSRQYEHQQFLTWLIEQIKDKQPHALLIAGDV
FDVINPASSAQKQLYQFLADAHSAAPHMQTLMIAGNHDSGYRLEQVEPLLEKYNAKTVGI
VRWNTEHRLDFDRLILPIHNEYQEIVAWCIALPFLRPAEITGHGEATQDSQQAIEYIHQA
LIKEALQRKTADQALILMSHAHMQGADESKESERPIIIGNHEALSTELFSPEIDYVALGH
LHKPQKVQSPHVRYSGSPIPLSFSELNYKHQVLEVNIDPDLSENRLEMNPLYIPRTVQLH
RLSGELDEVLTQLTLLPAGEISDIDQRDYLDIEYYSLTPPPPDLRKKIEDLLPPERYRLV
RISRKYLQQSSSEVHASKIDLAPPTPEQLFEQLWQKMGYSQDEQVKQDFMTLLQDAQQSE
HKMKTADNT