Protein Info for MPMX26_02247 in Acinetobacter radioresistens SK82

Annotation: Succinylglutamate desuccinylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 TIGR03242: succinylglutamate desuccinylase" amino acids 3 to 320 (318 residues), 440.2 bits, see alignment E=2.4e-136 PF04952: AstE_AspA" amino acids 44 to 320 (277 residues), 211.2 bits, see alignment E=9.8e-67

Best Hits

Swiss-Prot: 63% identical to ASTE_ACIBS: Succinylglutamate desuccinylase (astE) from Acinetobacter baumannii (strain SDF)

KEGG orthology group: K05526, succinylglutamate desuccinylase [EC: 3.5.1.96] (inferred from 63% identity to acd:AOLE_01820)

Predicted SEED Role

"Succinylglutamate desuccinylase (EC 3.5.1.96)" in subsystem Arginine and Ornithine Degradation (EC 3.5.1.96)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.96

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>MPMX26_02247 Succinylglutamate desuccinylase (Acinetobacter radioresistens SK82)
MVNLLALTLAQQTPEQIQGEAAGFTWQWLGEGLLQCTPKTAYRKTIVLSAGIHGNETAPI
ELLAQIIQDLFSGQLALAVRVLFVLGNPAAIRQGVRYLENDMNRMFCGAYQQLAQDGETQ
RAALLEQVTTQFFQQSQSNAQRYHYDLHTAIRESLLPVFALFPYQMQPYDDFLIQSLKAA
DLDALVYHNTAGKTFTHFTTERFQAASSTLELGKAKPFGQNDLAGFFSTDQMLRAALSGQ
ALPNRQKQDIRQFKVIDSILKINDDFKLNLSADAPNFSTFQPGEVIATQQAGSYVVQDQP
LWILFPNPEVKTGLRAGLILKEIK