Protein Info for MPMX26_02242 in Acinetobacter radioresistens SK82

Annotation: Potassium-transporting ATPase KdpC subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 201 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details PF02669: KdpC" amino acids 17 to 197 (181 residues), 229.6 bits, see alignment E=1.3e-72 TIGR00681: K+-transporting ATPase, C subunit" amino acids 18 to 198 (181 residues), 188.7 bits, see alignment E=5.3e-60

Best Hits

Swiss-Prot: 51% identical to KDPC_XANCP: Potassium-transporting ATPase KdpC subunit (kdpC) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01548, K+-transporting ATPase ATPase C chain [EC: 3.6.3.12] (inferred from 57% identity to acd:AOLE_06455)

MetaCyc: 47% identical to K+ transporting P-type ATPase subunit KdpC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (201 amino acids)

>MPMX26_02242 Potassium-transporting ATPase KdpC subunit (Acinetobacter radioresistens SK82)
MQILTQPVTQPAISTLIRPAIGLSLFALVVCGFGYSAIATKIGQAIFPEQAHGSLIKYEG
KVVGSKLVAQPFTAPSYFHSRPSVANYDPMALAGSNLARTNPELQKVIAERIVQVASLEA
IQPDQIPKDLVTASGSGIDPEISVQAALIQVKRIAEQRSMPEQQVRELVLKYAQQPTFGV
LGSNRVNVLELNLALDQLKRK