Protein Info for MPMX26_02117 in Acinetobacter radioresistens SK82

Annotation: Soluble pyridine nucleotide transhydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 PF07992: Pyr_redox_2" amino acids 15 to 334 (320 residues), 213 bits, see alignment E=4.3e-66 PF00890: FAD_binding_2" amino acids 16 to 54 (39 residues), 24.6 bits, see alignment 9.3e-09 PF12831: FAD_oxidored" amino acids 16 to 73 (58 residues), 33.4 bits, see alignment 2.2e-11 PF13450: NAD_binding_8" amino acids 19 to 55 (37 residues), 30.7 bits, see alignment 2e-10 PF00070: Pyr_redox" amino acids 186 to 259 (74 residues), 53.6 bits, see alignment E=1.8e-17 PF02852: Pyr_redox_dim" amino acids 353 to 462 (110 residues), 88.7 bits, see alignment E=2e-28

Best Hits

Swiss-Prot: 64% identical to STHA_MARMS: Soluble pyridine nucleotide transhydrogenase (sthA) from Marinomonas sp. (strain MWYL1)

KEGG orthology group: K00322, NAD(P) transhydrogenase [EC: 1.6.1.1] (inferred from 90% identity to acd:AOLE_05375)

MetaCyc: 58% identical to soluble pyridine nucleotide transhydrogenase (Escherichia coli K-12 substr. MG1655)
NAD(P)H oxidase. [EC: 1.6.3.1]; 1.6.3.- [EC: 1.6.3.1]; NAD(P)(+) transhydrogenase (B-specific). [EC: 1.6.3.1, 1.6.1.1, 1.6.1.3]

Predicted SEED Role

"Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1)" in subsystem Phosphate metabolism (EC 1.6.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.1.1 or 1.6.1.3 or 1.6.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (471 amino acids)

>MPMX26_02117 Soluble pyridine nucleotide transhydrogenase (Acinetobacter radioresistens SK82)
MPRKKEVVSGNFVKYDAVVLGSGPAGEGAAMKLAKAGKRVAIVDMREQLGGNCTHVGTIP
SKALRQTVSSIIRYQRDPMFKKVGDWKQFTMKQVLRNAHKVIQQQVDTHSRFYDRNKIDI
YHGRAYIQDKNTVLIFSDDGIKETLVFKQLVIATGSRPYHPAGLDFNHPRVFDSDKILDL
DFAIQKIIIYGAGVIGCEYASIFIGLDHKVDLINTQHKLLSYLDDEIADALSYHLREQGV
LIRHNEQIDYLETYDDHVVLHLQSGKKIKADAILWCNGRSGNTDGLGLENVGLTPNSRGQ
LAVNDQYQTEVENIYAAGDVVGWPSLASAAYDQGRCAGANMSGELNVKPVKDIPTGIYTI
PEISFFGKTEQELTEEKIPYEVGQASFRHLARAQITGDTVGELKLLFHRDTLELLGVHCF
GNNASEIIHIGQAVMQSPNNTLKYFIETTFNYPTMAEAYRVAALNGLNRLF