Protein Info for MPMX26_02107 in Acinetobacter radioresistens SK82

Annotation: Peptidoglycan glycosyltransferase MrdB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 transmembrane" amino acids 32 to 54 (23 residues), see Phobius details amino acids 66 to 83 (18 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 177 to 194 (18 residues), see Phobius details amino acids 200 to 219 (20 residues), see Phobius details amino acids 289 to 309 (21 residues), see Phobius details amino acids 322 to 349 (28 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details TIGR02210: rod shape-determining protein RodA" amino acids 33 to 380 (348 residues), 427.6 bits, see alignment E=1.9e-132 PF01098: FTSW_RODA_SPOVE" amino acids 37 to 379 (343 residues), 360.1 bits, see alignment E=6.4e-112

Best Hits

Swiss-Prot: 56% identical to RODA_SHIFL: Peptidoglycan glycosyltransferase MrdB (mrdB) from Shigella flexneri

KEGG orthology group: K05837, rod shape determining protein RodA (inferred from 88% identity to abc:ACICU_02516)

MetaCyc: 56% identical to peptidoglycan glycosyltransferase MrdB (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Rod shape-determining protein RodA" in subsystem Bacterial Cytoskeleton or Peptidoglycan Biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>MPMX26_02107 Peptidoglycan glycosyltransferase MrdB (Acinetobacter radioresistens SK82)
MSPSSQYKFLRQAPRDGLSTAMQPSRWQRLHIDPWLCLFLFLNALLGLTVLYSASAQDVG
LVSKQAMSFGIGFIVMFTLAQIPPKVYQAFSPYFYIFGVLALLSVMIFGEVRMGAQRWID
IPGFGSVQPSEFMKIGMPMMIAWFLSRHPLPPSFKNVIISLVLIIVPFLLIAEQPDLGTS
LLILASGLFVLFLSGLSWKLIGAAIGLMCMIIPLAWQFLLHDYQRQRVLTLLNPEADALG
TGWNIIQSKTAIGSGGFFGKGFLQGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILITL
YFAIIFRVLQIGLNCFHNYGRLVAGTLGLSFFVYVFVNAGMVSGILPVVGVPLPFMSYGG
TAIITLMATFGLVMSIHTHR