Protein Info for MPMX26_01867 in Acinetobacter radioresistens SK82

Annotation: Bifunctional uridylyltransferase/uridylyl-removing enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 888 TIGR01693: protein-P-II uridylyltransferase" amino acids 30 to 877 (848 residues), 892.1 bits, see alignment E=2.2e-272 PF01909: NTP_transf_2" amino acids 69 to 131 (63 residues), 21.1 bits, see alignment 6.9e-08 PF08335: GlnD_UR_UTase" amino acids 175 to 317 (143 residues), 149 bits, see alignment E=1.9e-47 PF01966: HD" amino acids 491 to 586 (96 residues), 33.9 bits, see alignment E=7e-12

Best Hits

Swiss-Prot: 87% identical to GLND_ACIAD: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 87% identity to aci:ACIAD2079)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (888 amino acids)

>MPMX26_01867 Bifunctional uridylyltransferase/uridylyl-removing enzyme (Acinetobacter radioresistens SK82)
MITTSPLLNYVKSNHDIQAINVWRTDVEKQLQESYENGQSIRDIILARSNLIDEALIFLW
QHAGLHQTDLGLFAVGGYGRREMLPYSDVDIMILSEDDITPEQESLISTFISSLWDVGNF
KPGISVRTIASCVEQATNDLTVATALIEARLITGNQHLARWPRRIVSQTWTDKTFFDAKM
QEQAKRYAQHNHTESNLEPDIKNAPGGIRDINQIGWIAKRHFRVNRIYDLVHLGFISEFE
LAVLEEAEIFLWEIRHHLHRLVKRDENRLLFDYQREIAAKFGYVHKEGESPNYPIEQFMK
RYYRTAQQVSTLNEMLLAYFNESVITPRLPSYERKIEEINEHFKLVDGKLAVQHHKIFSE
NPSAILEIFYLLANRPEIQGVRARTLRLLTLAAKRIDQSFRDNPMHQALFMAIIRSPYRL
YDTLVAMKRYGVLGKYIPSFGKITGLMQYDLFHIYTVDAHTLLLLRNLNRFKEPEFAKDF
PVVSSVFQRLARRDIVFLAALFHDIAKGRGGDHSELGAVDAIEFCRAHGFTERECKMVAW
LIQNHLLMSLTAQKKDISDPDVVKEFAEKLGDMEHLDYLYCLTVADINATNPKLWNTWRA
SLMRQLYTHARDVIRTGLGRPVEYQMLIEDTKFAASELLVDEFALEEVEKVWQELGDEYF
LKESANEIAWHTRAILQHGDNPAPLVLMRAHRKAAQDAVQIFIYTQDKPNLFATTVAVLD
RMNLDVQDARIITATKAFSLDTYVVLDRFGTLLTDAERKQTVADALVQALSHADNYPGLM
QRRIPRQLRHFDVKNTVDITLNPALQQNMVEISTLDQPGLLAKVGGLFMMQGLDIHSAKI
VTLGERAEDIFFVTKKDGTPMNAEEAQLFSAKLKSALDEASSQVISQH