Protein Info for MPMX26_01770 in Acinetobacter radioresistens SK82

Annotation: Ethanolamine ammonia-lyase heavy chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF06751: EutB" amino acids 12 to 443 (432 residues), 731.6 bits, see alignment E=1.6e-224

Best Hits

Swiss-Prot: 51% identical to EUTB_ECO57: Ethanolamine ammonia-lyase heavy chain (eutB) from Escherichia coli O157:H7

KEGG orthology group: K03735, ethanolamine ammonia-lyase large subunit [EC: 4.3.1.7] (inferred from 83% identity to acd:AOLE_06645)

MetaCyc: 51% identical to ethanolamine ammonia-lyase subunit alpha (Escherichia coli K-12 substr. MG1655)
Ethanolamine ammonia-lyase. [EC: 4.3.1.7]

Predicted SEED Role

"Ethanolamine ammonia-lyase heavy chain (EC 4.3.1.7)" in subsystem Ethanolamine utilization (EC 4.3.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.3.1.7

Use Curated BLAST to search for 4.3.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>MPMX26_01770 Ethanolamine ammonia-lyase heavy chain (Acinetobacter radioresistens SK82)
MRYQTTIAQQNYIFPDLKTLMAKASPLRSGDELAGIAAQNATERVAAQMALAEVPLKKFL
NEVLVDYETDEVTRLIIDEHDAQSFYPIAHFTVGDFRNWLLSAEATTEKLQALSPGLIPE
MVAAVSKIMRNQDLILVASKCEIITRFRNTVGLKGRLSTRLQPNHPTDDLLGISASILDG
LMYGNGDAVIGINPATDNLQNLSELLKLLDHIIQDYQIPTQSCILTHVSSGIHLANQNVP
VDLMFQSIAGTELANRGFGISLAMLQEGYEAALSLKRGTIGQNVMYFETGQGSALSSNAH
HGVDQQTIETRAYAVARKFNPFLVNTVVGFIGPEYLYNGKQIIRAGLEDHFCGKLMGLPM
GCDICYTNHADADQDDMDTLLTLLATAGINFIMGIPGSDDVMLNYQTTSFHDALYARQLL
GLQPAPEFAHWLEQQGILRQQHQQIEWAKQMPEQFSRLLQS