Protein Info for MPMX26_01160 in Acinetobacter radioresistens SK82

Annotation: Cytochrome bo(3) ubiquinol oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 transmembrane" amino acids 28 to 49 (22 residues), see Phobius details amino acids 69 to 93 (25 residues), see Phobius details amino acids 100 to 119 (20 residues), see Phobius details amino acids 138 to 164 (27 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details PF00510: COX3" amino acids 20 to 204 (185 residues), 50.7 bits, see alignment E=1.2e-17 TIGR02842: cytochrome o ubiquinol oxidase, subunit III" amino acids 24 to 206 (183 residues), 264.9 bits, see alignment E=2.5e-83

Best Hits

Swiss-Prot: 61% identical to CYOC_ECOL6: Cytochrome bo(3) ubiquinol oxidase subunit 3 (cyoC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02299, cytochrome o ubiquinol oxidase subunit III [EC: 1.10.3.-] (inferred from 88% identity to abb:ABBFA_001296)

MetaCyc: 61% identical to cytochrome bo3 subunit 3 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>MPMX26_01160 Cytochrome bo(3) ubiquinol oxidase subunit 3 (Acinetobacter radioresistens SK82)
MAEVLHHDNHGHDEHHHHDDTDITVFGFWTYLMSDLILFGTLFIAFAVLSSHVPPGTPSA
GDLFGDSLGFVLTETFALLISSVTFGFAVLASYKKNVGQVIAWLAVTWLFGASFIGMELY
EFNHLVHEGYGPTTSAFLSSFFTLVGTHGIHVTSGLVWMIILMIQIKKNGLTLPNMRRLA
CLSLFWHFLDIVWICVFSVVYLMGVL