Protein Info for MPMX26_01122 in Acinetobacter radioresistens SK82

Annotation: Amidophosphoribosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 TIGR01134: amidophosphoribosyltransferase" amino acids 2 to 466 (465 residues), 516.1 bits, see alignment E=5.4e-159 PF13522: GATase_6" amino acids 66 to 195 (130 residues), 56 bits, see alignment E=6.6e-19 PF13537: GATase_7" amino acids 80 to 213 (134 residues), 48.6 bits, see alignment E=1.2e-16 PF00156: Pribosyltran" amino acids 278 to 393 (116 residues), 37 bits, see alignment E=3.2e-13

Best Hits

Swiss-Prot: 71% identical to PUR1_PSEAE: Amidophosphoribosyltransferase (purF) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00764, amidophosphoribosyltransferase [EC: 2.4.2.14] (inferred from 89% identity to aci:ACIAD1323)

MetaCyc: 64% identical to amidophosphoribosyltransferase (Escherichia coli K-12 substr. MG1655)
Amidophosphoribosyltransferase. [EC: 2.4.2.14]

Predicted SEED Role

"Amidophosphoribosyltransferase (EC 2.4.2.14)" in subsystem De Novo Purine Biosynthesis (EC 2.4.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>MPMX26_01122 Amidophosphoribosyltransferase (Acinetobacter radioresistens SK82)
MCGVVGIAGKAPVNQMLFDALTMLQHRGQDAAGIVTCHEGRLFLRKDNGMVRDVFHTRHM
RALLGNYGIGHVRYPTAGSSSSAEAQPFYVNSPYGITLAHNGNLVNAKDIHEDLFKTDLR
HMNTDSDSEVLLNVFAHELQKSGKLEPCAEDIFHAVSRVHDRCKGAYGVVAMITGHGVVG
FRDPNGIRPLIYGSRETEEGTEYIIASESVAITALGFKIERDVAPGEAIFIDSQGQLFTQ
QCAKNPSYRPCIFEYVYFARPDAIIDGISVYKSRLRMGETLAAKILREWGENHDIDVVIP
IPDTSRTSALELANILGVKFREGFMKNRYIGRTFIMPGQQQRKKSVRQKLNPVELEFKGK
NVLLVDDSIVRGTTCNEIIQMARDSGAKQVFFASAAPEVMYPNVYGIDMPAKFELIASGR
SVEEVREIIGADRLIFQDLEDLKDAVRTKKVPHLTEFDCSVFDGIYVTGNIDEIYLEDLE
KLRNDMAKKGKDPYIDVNIDAASVDLTGIREE