Protein Info for MPMX26_01089 in Acinetobacter radioresistens SK82

Annotation: ATP phosphoribosyltransferase regulatory subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF13393: tRNA-synt_His" amino acids 12 to 322 (311 residues), 316.9 bits, see alignment E=7.3e-99 TIGR00443: ATP phosphoribosyltransferase, regulatory subunit" amino acids 15 to 324 (310 residues), 273.2 bits, see alignment E=1.4e-85

Best Hits

Swiss-Prot: 80% identical to HISZ_ACIBY: ATP phosphoribosyltransferase regulatory subunit (hisZ) from Acinetobacter baumannii (strain AYE)

KEGG orthology group: K02502, ATP phosphoribosyltransferase regulatory subunit (inferred from 80% identity to aby:ABAYE2593)

Predicted SEED Role

"ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)" in subsystem Histidine Biosynthesis (EC 2.4.2.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.2.17

Use Curated BLAST to search for 2.4.2.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (388 amino acids)

>MPMX26_01089 ATP phosphoribosyltransferase regulatory subunit (Acinetobacter radioresistens SK82)
MPISETWLLPDGVADVLPEQAQIIEKLRRKALDFLVSRGYQLVYTPFIEYIESLSSLSEA
NQDLDLATFKVIDQLTGRLLGIRADMTPQVARIDAHVRPVEGVARYCYAGTVLHTKPQGF
SATRAPLQLGAELFGSESIDADVEMVDLMISLIQKAGLTDGIHLDLGHVGLFRSLVKQAA
LNKATEHQLSDLYQRKALPELAEFTQTLHFGSDFYVLGRYASDLGALEANLSAEILKNAA
FKQAFDAVKTTQSEIQARWPNLHIGIDVVELRSYHYHTGLMYAVYAPNRAAPLAQGGRYD
GIGEHFGRARPATGFSCDLYALSAGQFNELSIVVAPKGTDTDLLKMIERLRTEGLSVVQL
LGQDDLSSVPNATHQLVQVAGHWNLEKI