Protein Info for MPMX26_01034 in Acinetobacter radioresistens SK82

Annotation: L-2,4-diaminobutyrate decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 PF00282: Pyridoxal_deC" amino acids 84 to 428 (345 residues), 207.3 bits, see alignment E=4.7e-65 PF01212: Beta_elim_lyase" amino acids 193 to 347 (155 residues), 35.5 bits, see alignment E=1.1e-12

Best Hits

Swiss-Prot: 91% identical to DDC_ACIBA: L-2,4-diaminobutyrate decarboxylase (ddc) from Acinetobacter baumannii

KEGG orthology group: K13745, L-2,4-diaminobutyrate decarboxylase [EC: 4.1.1.86] (inferred from 91% identity to abb:ABBFA_001004)

MetaCyc: 91% identical to diaminobutyrate decarboxylase (Acinetobacter baumannii AYE)
Diaminobutyrate decarboxylase. [EC: 4.1.1.86]

Predicted SEED Role

"L-2,4-diaminobutyrate decarboxylase (EC 4.1.1.86)" (EC 4.1.1.86)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.86

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (510 amino acids)

>MPMX26_01034 L-2,4-diaminobutyrate decarboxylase (Acinetobacter radioresistens SK82)
MVDFAEHRKALLCNDAQSIADYESAMEQATKAVAAWLQNDKMYTGGSIKELREAIAFHPS
KEGLGVQKSLERMVELFLNKSLKVHHPHSLAHLHCPTMVASQIAEVLINATNQSMDSWDQ
SPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMGVLLARDACIAKNWKDENGKP
WSVQRNGIPAEAMRNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
TMAHLQSEGKIVACVVATAGTTDAGAIDPLKQIREITNKYGAWMHIDAAWGGALILSNDY
RSMLDGIELSDSVTLDFHKHYFQTISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPN
LVSKSLQTTRRFDALKLWMTVEALGEELYGSMIDHGVKLTREVADYIKATDGLELLVEPQ
FASVLFRVVPAGYPAEFLDALNQNVADELFARGEANIGVTKVGQVQSLKMTTLSPVATLE
NVKNLLDLVLVEADRIKESIQQGSYTPPIA