Protein Info for MPMX26_01007 in Acinetobacter radioresistens SK82

Annotation: D-alanyl-D-alanine carboxypeptidase DacA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00768: Peptidase_S11" amino acids 28 to 260 (233 residues), 218.1 bits, see alignment E=1.3e-68 PF13354: Beta-lactamase2" amino acids 37 to 187 (151 residues), 54.4 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: K07258, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) [EC: 3.4.16.4] (inferred from 70% identity to aci:ACIAD1184)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>MPMX26_01007 D-alanyl-D-alanine carboxypeptidase DacA (Acinetobacter radioresistens SK82)
MRIFAYLFILFSLCCASLANARLLQVVPESVEAAAWSILDPQSGQIIAEYNSEVQRSPAS
LTKMMVAYIALKEIENGKLNRNEILTATPVVKMVMWDESQMYLKEGEQISVDQLLAGLIV
MSANDAAVTLAERISGNVPAFIERMNQEAQKLGMKNTHFTNPAGITMDGHYSTAHDLALL
GQALVNDTPDYLNYSKQQSFTYNNHFHRATNLLLKQDATVDGLKTGFTKAAGYNLALTAS
RPTMNADLPNRRLIVVVMGTTSAVKRAEVAYKLLNLGYAYTRDEVAIKDKQLLGELPVVK
STLKMFKVKSAQPKIITTSLYNQPYAIDLQTFDNATQRIMLNTGNGILQTIEPLQTTNTH
INIELNTKQLTAPLMQVMKLATVHVYQNNQLISTFDIENEVHIEEANFFQRIFLWLVSLF
PFMSNDEMKTAPEVFNS