Protein Info for MPMX26_00780 in Acinetobacter radioresistens SK82
Annotation: Phosphoenolpyruvate carboxykinase [GTP]
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 91% identical to PCKG_ACIAD: Phosphoenolpyruvate carboxykinase [GTP] (pckG) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
KEGG orthology group: K01596, phosphoenolpyruvate carboxykinase (GTP) [EC: 4.1.1.32] (inferred from 91% identity to aci:ACIAD2842)MetaCyc: 55% identical to cytosolic phosphoenolpyruvate carboxykinase (GTP) (Homo sapiens)
Phosphoenolpyruvate carboxykinase (GTP). [EC: 4.1.1.32]; 4.1.1.32 [EC: 4.1.1.32]
Predicted SEED Role
"Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)" in subsystem Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.32)
MetaCyc Pathways
- gluconeogenesis III (10/12 steps found)
- anaerobic energy metabolism (invertebrates, cytosol) (6/7 steps found)
- superpathway of anaerobic energy metabolism (invertebrates) (11/17 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.1.1.32
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (609 amino acids)
>MPMX26_00780 Phosphoenolpyruvate carboxykinase [GTP] (Acinetobacter radioresistens SK82) MTQVNAPEFVRHPKLIAWVEEIAKLTKPAKIEWCDGSDEEYQRLIDLMIANGTMKALNQE KHPGSYLANSDPSDVARVEDRTYICSEKQEDAGATNNWEAPAEMRTKLNGLFDGAMAGRT MYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMTKMARMGKAVYDVLGTDGEFIPCVHTVG APLAEGQKDVSWPCNKEKYIVHYPETREIWSYGSGYGGNALLGKKCLALRIASVMGRDQG WLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKP GEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTENGEVWWEGLSKEI PANLTTWKGQPHAEGEKAAHPNARFTVSAAQCPSIDADWENPAGVPISAFIFGGRRADTV PLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFGHWLSMG EKVAAQAEAHGNHLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRASAVETP IGYVPTYEQLNWTGLDFSKEQFDTVTSQDKDQWIKELESHTELFSKLGDRLPQALKDRQN QLLDAVKSV