Protein Info for MPMX26_00738 in Acinetobacter radioresistens SK82

Annotation: Phosphopantetheine adenylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 163 TIGR00125: cytidyltransferase-like domain" amino acids 5 to 63 (59 residues), 64.3 bits, see alignment E=8.7e-22 TIGR01510: pantetheine-phosphate adenylyltransferase" amino acids 6 to 158 (153 residues), 196.2 bits, see alignment E=3.2e-62 PF01467: CTP_transf_like" amino acids 7 to 135 (129 residues), 100.6 bits, see alignment E=8.6e-33 PF08218: Citrate_ly_lig" amino acids 13 to 69 (57 residues), 22.3 bits, see alignment E=9.5e-09

Best Hits

Swiss-Prot: 91% identical to COAD_ACIBY: Phosphopantetheine adenylyltransferase (coaD) from Acinetobacter baumannii (strain AYE)

KEGG orthology group: K00954, pantetheine-phosphate adenylyltransferase [EC: 2.7.7.3] (inferred from 90% identity to abm:ABSDF2584)

MetaCyc: 61% identical to pantetheine-phosphate adenylyltransferase (Escherichia coli K-12 substr. MG1655)
Pantetheine-phosphate adenylyltransferase. [EC: 2.7.7.3]

Predicted SEED Role

"Phosphopantetheine adenylyltransferase (EC 2.7.7.3)" in subsystem Coenzyme A Biosynthesis (EC 2.7.7.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (163 amino acids)

>MPMX26_00738 Phosphopantetheine adenylyltransferase (Acinetobacter radioresistens SK82)
MSKARVIYPGTFDPITNGHIDLVTRAAKMFDEVVVAIAIGHHKNPVFSLEERVALAKASL
SHLSNVEFVGFDGLLVNFFHEQKATAVLRGLRAISDFEYEFQLANMNRQLDPQFEAVFLT
PSEQYSFISSTLVREIARLKGDVNKFVPPAVVEAFKRKHQQGW