Protein Info for MPMX26_00616 in Acinetobacter radioresistens SK82

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03929: PepSY_TM
  • amino acids 7 to 390 (384 residues), 229.2 bits, E=2e-71
• PF00258: Flavodoxin_1
  • amino acids 418 to 543 (126 residues), 82.8 bits, E=5.4e-27
• PF00175: NAD_binding_1
  • amino acids 739 to 843 (105 residues), 40.5 bits, E=7.7e-14

Best Hits

KEGG orthology group: K00380, sulfite reductase (NADPH) flavoprotein alpha-component [EC: 1.8.1.2] (inferred from 70% identity to acd:AOLE_03205)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (11/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (8/9 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• assimilatory sulfate reduction I (3/4 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (6/10 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Protein Sequence (869 amino acids)

>MPMX26_00616 hypothetical protein (Acinetobacter radioresistens SK82)
MFKKTFFQVHWFLGITAGLILSIMGVTGAIYSYEQQILKWINQDSYVVQAEQRDKLTPAE
LYQHFHQQSPELKINSITVDTDPAASSTVNIEKKGERRGYNMMVNPYTAEVLPEIQGRKF
FQFIQQLHRNLTVGPVGKQITGACTLMLIFFVLSGLYLRWPKKHSWRQWFFIKPRLKGRN
FIWDLHAVVGTWVVIFYLILACTGLFWSYEWWRNGMFKVLGVEREQPALQGGNQPRGQEK
ELQASTGRSGGQQTGDREADRKRGQGLPPEQVQLALTQAWTGFNTQIGREYSSLTLTLPK
KPDGKIELSFTDAVPQHERARNKAVFDYRTSQLENLELYEDKKLNEKIMSSMLPVHRGSF
FGSVYQFLVMLAALAMPLFFVTGWMLYLKRRKQKKLTQAARNSSTAHSIDPNAKSWLITY
ATQTGMSEQLAWRTATSLQEARQPVTVKPIQQLHEADLKQAEHVLFVVSTYGTGEAPDLA
TGFVKKLMKSDLDLSHLNYAVLALGSQEYPDSYCSFGHEVNHWLKRSGAHPLFDVIEINN
GSNEDIQRWNQALARATRLDLSNMNIEKVFDQWILDKRELLNPGSLGRPAYNVELKAKHD
VIWQAGDIAEIQPGNSQARIQDFLNQHQLDGNTQVNSINMSLAEALWDRDLTGTVEVFNS
VDQLLEQLPALPSREYSIASIPSQQVLRLVVRQCEGADGLGLGTGWLTKHVPLHSPVALR
IRTNESFHLIDDNRPIICIGNGTGIAGLMSLLHSRVRQDYTQNWLIFGERQRNCDYFYQS
TLEAWQTTGMLQRLDLAFSRDQEQRIYVHHILREHSEELKNWIERGAVIYVCGSINGMAS
DVDQALIDILGECCVDDLRQNGRYRRDVY