Protein Info for MPMX26_00599 in Acinetobacter radioresistens SK82

Annotation: Holin-like protein CidB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 173 to 189 (17 residues), see Phobius details amino acids 198 to 221 (24 residues), see Phobius details PF04172: LrgB" amino acids 11 to 218 (208 residues), 156.6 bits, see alignment E=3.2e-50

Best Hits

KEGG orthology group: None (inferred from 83% identity to abm:ABSDF2858)

Predicted SEED Role

"LrgA-associated membrane protein LrgB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (222 amino acids)

>MPMX26_00599 Holin-like protein CidB (Acinetobacter radioresistens SK82)
MLMIIFGFLLTTVSYFCAKYLNQRFPQVPLLVFGMFIVVGLLALLQQPYEDYMQNVNPIF
NRLLGYVTVALAVPLAAMRYDDLPLKTMVGILVFASVSAVALPMTLAYLLHMSEPTVLAF
ATRAVTTPIALNIATLLHAPLTLVTLIVILSGVIGAAFSPLLLRHINDERASGLALGLAA
HAIGTAQAWQRGQVAGRYAAFGMAVNGVFTAIWLPTFLLYLQ