Protein Info for MPMX26_00300 in Acinetobacter radioresistens SK82

Annotation: 3-dehydro-bile acid delta(4,6)-reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07992: Pyr_redox_2" amino acids 5 to 177 (173 residues), 35.8 bits, see alignment E=1.8e-12 PF00070: Pyr_redox" amino acids 5 to 39 (35 residues), 22 bits, see alignment 5.6e-08 PF03486: HI0933_like" amino acids 5 to 392 (388 residues), 290.3 bits, see alignment E=6.7e-90 TIGR00275: flavoprotein, HI0933 family" amino acids 6 to 391 (386 residues), 255.7 bits, see alignment E=7.2e-80 PF13450: NAD_binding_8" amino acids 8 to 37 (30 residues), 23.5 bits, see alignment (E = 1.6e-08) TIGR03862: flavoprotein, TIGR03862 family" amino acids 26 to 398 (373 residues), 519.8 bits, see alignment E=3.6e-160

Best Hits

KEGG orthology group: K07007, (no description) (inferred from 69% identity to abn:AB57_0464)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (404 amino acids)

>MPMX26_00300 3-dehydro-bile acid delta(4,6)-reductase (Acinetobacter radioresistens SK82)
MSAKRIAIIGAGPAGLMAAEVLSRYAYEIHVFEQKPSAARKFLMAGKTGLNISHAEPLTE
FIQRYDHPEWLYPWIQRWDAHWIQNWIAELGIASYIGSSGRIFPVEMKAAPLLRAWLTRL
DQQGIHFHYRHQCLGLKAKQVQLLDLKQPENTPFQLEFDAIILACGAVSWPQLGSDGKWQ
AWLDREQIEPFQPSNAGVVRTWSSFMQPLLGQPLKRVEAWVSPKHRAQGDVVISHYGLES
GLIYKHGPALRKLQRQQQPVTLYLDLLPDVDNEQLIKKLQSGKQSLSNVWRKAGLDAAKA
GLIRELVDKTLWKDPVQLAWQVKHLKVVLEGFRPIEEAISCAGGIKQNALTARLQLKSKP
HVFCCGEMLDWDAPTGGYLLTACFATGRAAGEGVHTYLMEQQSS