Protein Info for MPMX26_00041 in Acinetobacter radioresistens SK82

Annotation: Non-hemolytic phospholipase C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR03396: phospholipase C, phosphocholine-specific" amino acids 2 to 717 (716 residues), 941.1 bits, see alignment E=2e-287 PF04185: Phosphoesterase" amino acids 45 to 454 (410 residues), 376.8 bits, see alignment E=1.2e-116 PF05506: PLipase_C_C" amino acids 527 to 612 (86 residues), 88.3 bits, see alignment E=5.2e-29 amino acids 623 to 703 (81 residues), 37.8 bits, see alignment E=3.1e-13

Best Hits

KEGG orthology group: K01114, phospholipase C [EC: 3.1.4.3] (inferred from 80% identity to abn:AB57_0084)

Predicted SEED Role

"Phospholipase C 4 precursor (EC 3.1.4.3)" (EC 3.1.4.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.4.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (720 amino acids)

>MPMX26_00041 Non-hemolytic phospholipase C (Acinetobacter radioresistens SK82)
MDRREFLLTTSKTLFGTAALASFPLSIQKALAIDAKVETGTLQDVKHVVILTQENRSFDN
YFGTLKGVRGFGDRFTIPLKEGRSVWEQYDAQQNKILPYHLDSTKGNAQRVSGTPHSWSD
GQAAWDHGRMGDWVKHKQPQSMGYYKKQELEYQFALADAFTICDAYHCAMHAGTNPNRKF
IWTGTNGPTGAGVASVVNEFDGLGPSSEGYEWSTYPERLQQAGVSWKVYQNMPDNFTDNP
LAGFKQYRRANEQSGQPVSHSDLKSPAYDARIDASQPLYKGIANTMPDGGFLGSFKEDIQ
QGQLPQVSWIVAPATYSEHPGPSSPVQGAWYIQEVLNALTENPHIWSQTVLLVNFDENDG
FFDHIPSPSAPSKDQTGQLQGKTTLTEQQLSYEYFNHPAVAGSKSQPKPDGRVYGPGVRV
PLYILSPWSRGGWVNSQVFDHTSILRFLEQRFGIQEPNISPYRRAVCGDLTSAFNFKTPN
LDILPELPGQKSRQEADAIRLRQALLPQLTVPKNQNMPLQQTGIRLSRALPYILHCSAKV
ELARQQVQLIFSNTGEQAAVFHVYNKLDLEAIPRRYMVEAGKQLDDIWSVHDGRYDLWVL
GPNGFHRSFQGNLHSKLYSESLPEIRICVEECEPKIYLKLRSDGQKTVKLVIQANAYLNK
SWHIETRAAETELLLDMSEWYGWYDFTVSLENEPEFKRRFAGRIETGKDSYSDPFMGYSV